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Simona Pinzaru

Universitatea Babes-Bolyai, Cluj-Napoca, Romania

Institution web page: http://www.phys.ubbcluj.ro, http://phys.ubbcluj.ro/cercetare/granturi/pinzaru/english/index_en.htm
Personal web page: http://phys.ubbcluj.ro
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Born: 1965

Interests: Raman spectroscopy, tissue diagnostic, nanomaterials, biomaterials, optical biosensors, biospectroscopy, biomaterials, HIV-inhibitors, new pharmaceutical compoounds, food additives, micro-Raman, surface-enhanced Raman spectroscopy (SERS), surface-enhanced infrared absorption (SEIRA)

Details:
Researcher ID: A-4543-2011
Profile URL : http://www.researcherid.com/rid/A-4543-2011



Projects concerning the applications of Raman and surface enhanced Raman spectroscopy in the study of biological systems;
New techniques for tissue monitoring, evidencing the pollutants in human body or environment; Optical biosensors, surface plasmon resonances, pharmaceuticals, biomaterials

ResearcherID: A-4543-2011

Selected publications:
• Csilla Müller, Branko Glamuzina, Iva Pozniak, Karina Weber, Dana Cialla, Jürgen Popp, Simona Cinta Pinzaru. Amnesic shellfish poisoning biotoxin detection in seawater using pure or amino-functionalized Ag nanoparticles and SERS. TALANTA, 130, p. 108, 2014.
• Csilla Müller, Leontin David, Vasile Chis, Simona Cinta Pinzaru. Detection of thiabendazole applied on citrus fruits and bananas using surface enhanced Raman scattering. Food Chemistry, 145, pp. 814-820, 2014.
• Simona Cinta Pinzaru, * Alexandra Falamas, Cristina Dehelean, Cristian Morari, and Monica Venter. Double Amino Functionalized Ag Nanoparticles as SERS Tags in Raman Diagnostic. Croatica Chemica Acta, 86(3), pp. 233-244, 2013.
• Csilla Müller, Leontin David and Simona Cinta Pinzaru. Detection of thiabendazole applied to organic fruit by near infrared surface-enhanced Raman spectroscopy. Spectroscopy Europe, 25 (4), p. 6, 2013.
• Simona Cinta Pinzaru, C. A. Dehelean, A. Falamas, C. Soica, S. Ciurlea, C. Danciu. Cellular events in four B16 melanoma cell lines revealed by SERS. In Beat Loffler, Patrik Hunziker (eds.), 6/2013 CLINAM Conference Proceedings, 6, pp. 208-210. H. Leidenfrost AG , 2013.
• Cinta Pinzaru, S., Falamas, A. and Dehelean, C. A. Molecular conformation changes along the malignancy revealed by optical nanosensors. Journal of Cellular and Molecular Medicine, 2013.
• Gui, O. M., Falamas, A., Barbu-Tudoran, L., Aluas, M., Giambra, B. and Cinta Pinzaru, S. Surface-enhanced Raman scattering (SERS) and complementary techniques applied for the investigation of an Italian cultural heritage canvas. Journal of Raman Spectroscopy, 44, pp. 277-282, 2013.
• Simona Cinta-Pinzaru, Cristina A Dehelean, Codruta Soica, Monica Culea and Florin Borcan. Evaluation and differentiation of the Betulaceae birch bark species and their bioactive triterpene content using analytical FT-vibrational spectroscopy and GC-MS. Chemistry Central Journal, 6(67), 2012.
• A. Falamas, S. Cinta Pinzaru, C. A. Dehelean, M. M. Venter. Raman Imaging of In Vivo Damaged Skin Tissues from Mice Specimens. Studia Chemia UBB , 2, pp. 273-283, 2010.
• A. Falamas, S. Cinta Pinzaru, C. A. Dehelean, C. I. Peev, C. Soica. Betulin and its natural resource as potential anticancer drug candidate seen by FT-Raman and FT-IR spectroscopy. Journal of Raman Spectroscopy, DOI: 10.1002/jrs.2658, 2010.
• I. Hubert Joe, Irena Kostova, C. Ravikumar, M. Amalanathan, and Simona Cinta Pinzaru. Theoretical and vibrational spectral investigation of sodium salt of acenocoumarol. Journal of Raman Spectroscopy, 40(8), pp. 1033 - 103, 2009.
• Simona Cinta Pinzaru. Book Review: RAMAN AND SERS INVESTIGATIONS OF PHARMACEUTICALS, Authors: M. Baia, S. Astilean, T. Iliescu. Journal of Raman Spectroscopy, 40(6), p. 709, 2009.
• Simona Cinta Pinzaru*, Bogdan P. Onac. Raman study of natural berlinite from a geological phosphate deposit. Vibrational Spectroscopy , 49, pp. 97-100, 2009.
• S. Cinta Pinzaru, L. M. Andronie, I. Domsa, O. Cozar and S. Astilean. Bridging biomolecules with nanoparticles: surface-enhanced Raman scattering from colon carcinoma and normal tissue. Journal of Raman Spectroscopy, 39(3), p. 331, 2008.
• S. Cinta Pinzaru, N. Peica, U. Schmidt, W. Kiefer. New substrate sample handling and micro-Raman sensing methods for biomolecular analysis. J Optoelectr. Adv. Mat. , 9(3), pp. 764-768, 2007.
• I. Kostova, N. Trendafilova, S. Cinta Pinzaru, W. Kiefer, G. Momekov. Spectroscopic evidence of La(III) complex of coumarin-3-carboxylic acid with cytotoxic activity. J Optoelectr. Adv. Mat. 9, 3, 2007, 532-539, 9(3), pp. 532-539, 2007.
• S. Cavalu, S. Cinta Pinzaru, N. Peica, G. Damian, W. Kiefer. Adsorption behavior of hyaluronidase onto silver nanoparticles and PMMA bone substitute. J Optoelectr. Adv. Mat. , 9(3), pp. 689-693, 2007.
• C. A. Dehelean, S. Cinta Pinzaru, C. I. Peev, C. Soica, D. S. Antal. Characterization of birch tree leaves, buds and bark dry extracts with antitumor activity. J Optoelectr. Adv. Mat. , 9(3), pp. 783-787, 2007.
• Cristina A. Dehelean, C. Tatu, S. Cinta-Pinzaru, C. Peev, Soica Codruta, Tanasie Gabriela, S. Anghel. In vitro studies on mesenchimal stem cells of a dry birch tree bark extract. In Abstracts/Toxicology Letters 164S Proceedings of the EUROTOX 2006, Dubrovnic, Croatia, p. S228. 2006.
• S. Cinta Pinzaru, L. M. Andronie, N. Peica O. Cozar, W. Kiefer. ATR-FT-IR and micro-Raman spectroscopy of the colon carcinoma tissues. Proceedings of the XX International Conference on Raman Spectroscopy (ICORS 2006), Yokohama, Japan, p. 383, 2006.
• S. Cavalu, S. Cinta Pinzaru, G. Damian. Structural information, unfolding and aggregation in globular proteins, by Raman, SERS, FT-IR and complementary EPR spectroscopy. In R. K. Soni, et al (eds.), Proceedings ICOPVS 2006, International Conference on Perspectives in Vibrational Spectroscopy, Meerut, India, p. 3. Anita Publ. New Delhi, 2006.
• Simona Cinta Pinzaru, N. Peica, B. Küstner, S. Schlücker, M. Schmitt, T. Frosch, J. Popp. Raman and SERS spectroscopy in antimalaria research monitoring the interaction mechanism of quinoline based drugs with hematin. In R. K. Soni, et al (eds.), Proceedings ICOPVS, International Conference on Perspectives in Vibrational Spectroscopy, Meerut, India, , p. 4. Anita Publ. New Delhi, 2006.
• Cristina Adriana Dehelean, Camelia Peev, Simona Cinta-Pinzaru, Codruta Soica, Adriana Kaicsa. FT-IR, FT-Raman and TLC Densitometry Analysis of some Plane Tree Extracts Concerning their Content in Betulinic Acid and Betulin. Revista de Chimie, 57, 11, 2006.
• I. Pavel, S. Cota, S. Cinta-Pinzaru, Wolfgang Kiefer. SERS substrate-dependent interaction of the anticarcinogenic drug, 5-fluorouracil with silver. Particulate Science and Technology, 24 (3), pp. 301-309, 2006.
• Bogdan P. Onac, Herta Effenberger, Karl Ettinger and Simona Cinta Pinzaru. Hydroxylellestadite from Cioclovina Cave (Romania): Microanalytical, Structural, and Vibrational Spectroscopy Data. American Mineralogist, 91, pp. 1927-1931, 2006.
• S. Cinta Pinzaru, N. Peica, B. Küstner, S. Schlücker, M. Schmitt, T. Frosch, J. H. Faber, G. Bringmann and J. Popp. FT-Raman and NIR-SERS characterization of the chloroquine and mefloquine antimalarial drugs and their interaction with hematin. J. Raman Spectrosc. , 37, pp. 326-334, 2006.
• I. Pavel, S. Cota, S. Cinta Pinzaru, W. Kiefer. Raman, surface enhanced Raman spectroscopy and DFT calculations- a powerful approach for the identification and characterization of 5-fluorouracil anticarcinogenic drug species. J. Phys. Chem. A, 109(44), pp. 9945-9952, 2005.
• N. Peica, I. Pavel, S. Cinta Pinzaru, V. K. Rastogi and W. Kiefer. Vibrational characterization of E102 food additive by Raman and surface-enhanced Raman spectroscopy and theoretical studies. J. Raman Spectrosc. , 36, pp. 657-666, 2005.
• Nicolae Leopold, Simona Cinta-Pinzaru, Monica Baia, Elisabeta Antonescu, Onuc Cozar, Wolfgang Kiefer, Jürgen Popp. Vibrational Characterization of thiamine. The pH influence monitored by Raman and SERS spectroscopy. Vibr. Spectrosc. , 39(2), pp. 169-176, 2005.
• A. V. Szeghalmi, L. Leopold, S. Pinzaru, V. Chis, I. Silaghi-Dumitrescu, M. Schmitt, J. Popp, W. Kiefer. Adsorption of 6-Mercaptopurine-Riboside on Silver Colloid: A pH Dependent Surface Enhanced Raman Spectroscopy and Density Functional Theory Study. II. 6-Mercaptopurine -Ribose. Biopolymers, 78, pp. 298-310, 2005.
• A. V. Szeghalmi, L. Leopold, S. Pinzaru , V. Chis, I. Silaghi-Dumitrescu, M. Schmitt, J. Popp, W. Kiefer. Adsorption of 6-Mercaptopurine and 6-Mercaptopurine-Riboside on Silver Colloid: A pH Dependent Surface Enhanced Raman Spectroscopy and Density Functional Theory Study. Part I. 6-Mercaptopurine. J. Mol. Str. , 735-736, pp. 103-113, 2005.
• I. Pavel, S. Cinta-Pinzaru and W. Kiefer. Why SERS and DFT? A combination that can certainly help in analayzing pharmaceutical materials and their behavior near a biological artificial model. Proc. XIXth Intern. Conf. Raman Spectroscopy, Eds. , (2004), p. 356-357. , pp. 356-357, 2004.
• S. Cinta Pinzaru, N. Leopold, N. Peica and W. Kiefer. Monitoring the sweetener content in leaves of stevia rebaudiana plant using Raman and SERS spectroscopy. In P. M. Fredericks, R. L. Frost and L. Rintoul (eds.), Proc. XIXth Intern. Conf. Raman Spectroscopy, , pp. 419-420. CSIRO Publishing, Australia, 2004.
• S. Cinta Pinzaru, I. Pavel, N. Peica, N. Leopold. Concentration dependence Raman and SERS spectra of E 102 Food Additive. Asian Chem. Lett. , 8/1, pp. 39-44, 2004.
• S. Cinta-Pinzaru, I. Pavel, N. Leopold and W. Kiefer. Identification and characterisation of pharmaceuticals using Raman and surface enhanced Raman scattering. J. Raman Spectroscopy, 35, pp. 338-346, 2004.
• S. Cinta Pinzaru , N. Leopold , I. Pavel and W. Kiefer. Raman, SERS and Theoretical Studies of Papaverine Hydrochloride and its Neutral Species. Spectrochimica Acta A, 60/8-9, pp. 2021-2028, 2004.
• I. Pavel, A. Szeghalmi, D. Moigno, S. Cinta Pinzaru, W. Kiefer. Theoretical and pH dependent surface enhanced Raman spectroscopy study on caffeine. Biopolimers (Biospectroscopy), 72, pp. 25-37, 2003.
• I. Pavel, D. Moigno, S. Cinta Pinzaru, W. Kiefer. Surface enhanced Raman spectroscopy and theoretical studies on 1, 4 dihydrazinophthalazine sulfate. J. Phys. Chem. A, 106(14), pp. 3337-3344, 2002.
• Simona Cinta Pinzaru, N. Leopold, W. Kiefer. Vibrational spectroscopy of betulinic acid HIV inhibitor and of its birch bark natural source. Colloquium Spectroscopicum Internationale, CSI XXXII, Pretoria, South Africa, Vol. Abstracts, TH 4-4, 2001. Talanta, 57/4, pp. 625-631, 2002.
• S. Cinta Pinzaru, S. Cavalu, N. Leopold, R. Petry, W. Kiefer. Raman and surface enhanced Raman spectroscopy of tempyo spin labelled ovalbumin. J. Mol. Struct. , 565-566, pp. 225-229, 2001.
• S. Cavalu, S. Cinta Pinzaru, N. Leopold, W. Kiefer. Raman and Surface enhanced Raman spectroscopy of tempyo labelled proteins: bovine serum albumin and cytochrome c. Biopolimers/Biospectroscopy, 62, pp. 341-348, 2001.
• S. Cinta Pinzaru, M. Venter, T. Iliescu, O. Cozar, I. Haiduc, W. Kiefer. SERS APPLICATION IN ELUCIDATION OF THE NATURE OF HOMOLOGUE CU(I) TRIAZENIDO COMPLEXES. Vibrational Spectroscopy, 19, pp. 223-226, 1999.

Publications from the ISI database, indexed between 2002-2011, produced in Romania:
• Szeghalmi, AV; Leopold, L; Pinzaru, S; Chis, V; Silaghi-Dumitrescu, I; Schmitt, M; Popp, J; Kiefer, W, Adsorption of 6-mercaptopurine and 6-mercaptopurine-riboside on silver colloid: A pH-dependent surface-enhanced Raman spectroscopy and density functional theory study. II. 6-Mercaptopurine-riboside. BIOPOLYMERS, 78 (6), pp. 298-310, 2005.
• Szeghalmi, AV; Leopold, L; Pinzaru, S; Chis, V; Silaghi-Dumitrescu, I; Schmitt, M; Popp, J; Kiefer, W, Adsorption of 6-mercaptopurine and 6-mercaptopurine riboside on silver colloid: a pH dependent surface enhanced Raman spectroscopy and density functional theory study. Part I. 6-Mercaptopurine. JOURNAL OF MOLECULAR STRUCTURE, 735, pp. 103-113, 2005.
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