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Marius Paul Cirlan

Universitatea Apollonia Iasi, Iasi, România

Pagina web personală: http://www.mutmice.go.ro
Trimite un email

Născut(ă) în 1938

Interese: genetica, gena, mamifere domestice, soarece de laborator, mutatie, boli genetice umane

Detalii:
Curriculum vitae
First name: Marius Paul
Last name: Cirlan
Date of birth: 29.03.1938
Personal address: Str. V. Alecsandri 7, ap. 1,
700054 Iasi,Romania
Home phone number: +40-232-311272
e-mail: cirlanm2000@yahoo.com

Profession: veterinary doctor
Graduate of University of Agricultural Sciences and Veterinary medicine, Faculty of Veterinary Medicine Iasi, Romania 1968
Ph.D. thesis 1976 - University of Agricultural Sciences and Veterinary Medicine Iasi, Romania

1992-2004 Professor of Genetics at Faculty of
Veterinary Medicine Iasi, Romania
2004 - Professor of Genetics at Apollonia
University,Faculty Of Dental Medicine
Iasi,Romania

Research activity
During the last 10 years mutant laboratory mice were my principal topic of study. I have a colony of mutant mice consisting mainly of 3 novel mutants which I identified and named them. They are:
- Iasi congenital atrichia registered in data basis of Jackson Laboratory USA, and accessed on
www.informatics.jax.org
- Iasi hereditary jaundice
- Iasi total atrichia
These mice are studied in collaboration with Institut Pasteur Paris, Hamburg University, Children's Hospital Boston USA
The colony could be visited with a click on
www.mutmice.go.ro
Scientific activity by collaboration with foreign institutes and universities

- Program of collaboration with Laboratoire de Genetique biochimique et de Cytogenetique, Centre de Recherches de Jouy en Josas,INRA,France
for common investigations regarding Y chromosome in domestic ruminants(1998-2001). As part of this agreement I worked 2 months with an INRA scolarship in Laboratoire de Cytogenetique,Jouy en Josas,France.
-Collaboration with Institut Pasteur Paris, Unite de Genetique des Mammmiferes(head: dr. J.L.
Guenet)for mapping the mutant gene of Iasi congenital atrichia(1999-2004).
-Collaboration with Hamburg University, Department of Dermatology(head: prof.dr. Ralf Paus) for histopathologic studies of hair follicle abnormal growth in mutant mouse with Iasi congenital atrichia(2001-2006).
-Collaboration with Children's Hospital Boston,
USA(prof dr. Mark Fleming) for mapping the mutant gene of Iasi hereditary jaundice(2004-2006).

International partnerships

Associate partner in the PRIME European project(Priorities for Mouse Functional Genomics Research in Europe,March 2005-February 2008)

Invited conferences

1.Invited speaker at the Second European Conference of Cytogenetics held in Vienna,6-8 June 1999 with the scientific communication:
"Haploid-diploid chimerism in 1-day chickens with crossed beak accompanied by microphthalmia and/or anophthalmias".
2.Invited at French Workshop: Le chromosome Y: cytogenetique et biologie moleculaire" where I sustained the lecture:"La cytogenetique comparee du chromosome Y"

Selected books and chapters in books

1.Cirlan M. 1996 - Elemente de Genetica Animala
Normala,Ed. Polirom Iasi,280 pag.
Elements of Normal Animal Genetics
Ed. Polirom Iasi, Romania(in Romanian
2.Cirlan M. 1997 - Elemente de Genetica Animala
Patologica,Ed. Polirom Iasi,327 pag
Elements of Pathologic Animal
Genetics,Ed. Polirom Iasi, Romania(in
Romanian)
3.Cirlan M.,Creanga St. 2001- Evolutia
determinismului genetic al sexelor,
Ed. Sedcom Libris Iasi, 286 pag.
Evolution of Genetic Determinism of
Sexes, Ed. Sedcom Libris,Iasi,Romania
(in Romanian)
4.Cirlan M. 2001 - Clonarea animalelor si
consecintele ei, Ed. Junimea Iasi,88
pag.
Animal Cloning and its Consequences,
Ed. Junimea Iasi, Romania(in Romanian
5.Cirlan M. 2003 - Evolutia sexelor. Cromozomii
sexuali si genele sexualizante.
Capitol in "Genomica" sub redactia
L. Gavrila,Ed. Enciclopedica,
Bucuresti,567-592
Evolutiuon of Sexes. Sex Chromosomes
and Sexualizing Genes. Chapter in
"Genomics" edited by L. Gavrila,Ed.
Enciclopedica,Bucharest,Romania(in
Romanian)
6.Cirlan M. 2004 - Genetica Animala vol I, Ed.
Alfa,Iasi,335 pag.
Animal Genetics vol I,Ed. Alfa Iasi
(in Romanian)

Selected papers

1.Cirlan M. 1996 - A new allele at the mouse
hairless locus: hrnk. Mouse Genome 94
686-688
2.Cirlan M. 1997 - Tumoral and bone marrow
karyotypic profiles in mouse with
metastatic hemangiosarcoma. Cytogenet
Cell Genet. 77, pg 150(Abstracts of
papers,First European Cytogenetics
Conference,Athens,Greece).
3.Cirlan M. 2001 - Comparative gene distribution
of mouse and bull Y chromosome.
Annales de Genetique 44,suppl. 1,pg
37(Abstracts of papers,Third European
Cytogenetics Conference,Paris,france)
4.Cirlan M.,Cirlan A.F.,Balmus G. 2004 - Clonal
evolution of a mouse metastatic
hemangiosarcoma
Analele Stiintifice ale Universitatii
"Al.I. Cuza" Iasi,Genetica si
biologie moleculara,tom V,262-266(in
English).
5.Mecklenburg L.,Tobin D.J.,Cirlan M.,Craciun C.,
Paus R. 2005 - Premature termination
of hair follicle morphogenesis and
accelerated hair follicle cycling in
Iasi Congenital Atrichia(fzica/fzica)
mice points to fuzzy as a key element
of hair cycle control.
Experimental Dermatology, in press,
accepted for publication at 27.04.oo5










Publicații relevante:
• Lars Mecklenburg, Desmond J. Tobin, Marius V. Cirlan, Constantin Craciun, Ralf Paus. Premature termination of hair follicle morphogenesis and accelerated hair follicle cycling in Iasi congenital atrichia(fz ica) mice points to fuzzy as a key element of hair cycle control. Experimental Dermatology, 14, pp. 561-570, 2005.
• Marius Cirlan. Comparative gene distribution of mouse and bull Y chromosome. Annales de Genetique(Abstracts of papers, Third European Cytogenetics Conference, Paris, July 7-10 2001), vol. 44 - suppl. 1, p. pp. 37, 2001.
• Marius Cirlan. Haploid-diploid chimerism in 1-day chickens with crossedbeak accompanied by microphthalmia and/or anophthalmia. Cytogenetics and Cell Genetics(Abstracts of papers, Second European Cytogenetics Conference, Vienna, Austria, July 3-6, 1999), vol. 85, p. p. 17, 1999.
• Marius Cirlan. Tumoral and bone marrow karyotypic profiles in a mouse with metastatic hemangiosarcoma. Cytogenetics and Cell Genetics(Abstracts of the 1st European Cytogenetics Conference, Athens, Greece, June 22-25, 1997), vol. 77, p. p. 150, 1997.
• Marius Cirlan. A new allele at the m ouse hairless locus: hrnk. Mouse Genome, vol. 94, pp. 686-688, 1996.
• Victoria Zinca, Marius Cirlan. The reproduction of hormonal effects by macromolecular RNA. Acta Cytologica, vol. 13, pp. pp. 679-68, 1969.


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