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Gabriel Balmus

University of Cambridge, Cambridge, England

Personal web page: http://www.sanger.ac.uk/people/directory/balmus-gabriel
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Born: 1980

Interests: cancer research, rare diseases

Details:
Interested in the DNA damage response and the connection to disease

Selected publications:
• G Balmus, PX Lim, A Oswald, KR Hume, A Cassano, J Pierre, A Hill, W Huang, A August, T Stokol, T Southard, RS Weiss. HUS1 regulates in vivo responses to genotoxic chemotherapies. Oncogene, 2015.
• Gabriel Balmus, Natasha A Karp, Bee Ling Ng, Stephen P Jackson, David J Adams, Rebecca E McIntyre. A high-throughput in vivo micronucleus assay for genome instability screening in mice. Nature protocols, 10(1), 2015.
• Gabriel Balmus, Rebecca E McIntyre. Genetic screens in mice for genome integrity maintenance and cancer predisposition. Current opinion in genetics & development, 24, 2014.
• Sachiyo Okayama, Levy Kopelovich, Gabriel Balmus, Robert S Weiss, Brittney-Shea Herbert, Andrew J Dannenberg, Kotha Subbaramaiah. p53 protein regulates Hsp90 ATPase activity and thereby Wnt signaling by modulating Aha1 expression. Journal of Biological Chemistry, 289(10), 2014.
• Gabriel Balmus, Min Zhu, Sucheta Mukherjee, Amy M Lyndaker, Kelly R Hume, Jaesung Lee, Mark L Riccio, Anthony P Reeves, Nathan B Sutter, Drew M Noden, Rachel M Peters, Robert S Weiss. Disease severity in a mouse model of ataxia telangiectasia is modulated by the DNA damage checkpoint gene Hus1. Human molecular genetics, 21(15), 2012.
• Erin K. Daugherity, Gabriel Balmus, Ahmed Al Saei, Elizabeth S. Moore, Delbert Abi Abdallah, Arlin B. Rogers, Robert S. Weiss, Kirk J. Maurer. The DNA damage checkpoint protein ATM promotes hepatocellular apoptosis and fibrosis in a mouse model of non-alcoholic fatty liver disease. Cell Cycle, 11(10), 2012.
• J Kim Holloway, Swapna Mohan, Gabriel Balmus, Xianfei Sun, Andrew Modzelewski, Peter L Borst, Raimundo Freire, Robert S Weiss, Paula E Cohen. Mammalian BTBD12 (SLX4) protects against genomic instability during mammalian spermatogenesis. PLoS Genet, 7(6), 2011.
• Gabriel Balmus, Vladimir A Trifonov, Larisa S Biltueva, Patricia CM O’Brien, Elena S Alkalaeva, Beiyuan Fu, Julian A Skidmore, Twink Allen, Alexander S Graphodatsky, Fengtang Yang, Malcolm A Ferguson-Smith. Cross-species chromosome painting among camel, cattle, pig and human: further insights into the putative Cetartiodactyla ancestral karyotype. Chromosome Research, 15(4), 2007.


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