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Mihail Coculescu

Universitatea de Medicina si Farmacie " Carol Davila" , Bucuresti, Romania

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Born: 1943

Interests: endocrinology, neuroendocrinology, pituitary, pineal, vasopressin, vasotocin, diabetes insipidus, metabolic syndrome, insulin resistance, polykistic ovary syndrome, blood-brain barrier, sleep

Fellow of the Academy of Medical Sciences,Romania(1993), President of Section for Basic Medical Sciences (2011)
Founder(1990) and President of the Romanian Society of PsychoneuroEndocrinology(RPNES),1990-1997) and President of Honour (1998-ad vitam)for RPNES
Fellow of the American College of Endocrinology (1997), International Clinician Award of ACE (2002)
Fellow of the Royal College of Physicians (London 1996)
Editor-in-Chief, Acta Endocrinologica (Bucharest),the International Journal of the Romanian Society of Endocrinology
Professor of Endocrinology, University of Medicine and Pharmacy"Carol Davila",Bucharest,(1994),prorector of the university (2000-2008) head of department of endocrinology
National Institut of Endocrinology "C.I.Parhon", Romania, Scientific Director(1997-2007), head of section for pituitary diseases and neuroendocrinology (1997-2011)

ResearcherID: D-7162-2011

Selected publications:
• Biller BM, Ji HJ, Ahn H, Savoy C, Siepl EC, Popovic V, Coculescu M, Roemmler J, Gavrila C, Cook DM, Strasburger CJ. . Effects of once-weekly sustained-release growth hormone: a double-blind, placebo-controlled study in adult growth hormone deficiency. . Journal of Clinical Endocrinology and Metabolism . Epub 2011 Mar 16. , 96(6), pp. 1718-1726, 2011.
• Hanzu FA, Radian S, Attaoua R, Ait-El-Mkadem S, Fica S, Gheorghiu M, Coculescu M, Grigorescu F. . Association of insulin receptor genetic variants with polycystic ovary syndrome in a population of women from Central Europe. . Fertil Steril. Epub 2010 May 20. , 94(6), pp. 2389-2392, 2010.
• Raica M, Coculescu M, Cimpean AM, Ribatti D. . Endocrine gland derived-VEGF is down-regulated in human pituitary adenoma. Anticancer Res. , 30(10), pp. 3981-3986, 2010.
• Attaoua R, Ait El Mkadem S, Radian S, Fica S, Hanzu F, Albu A, Gheorghiu M, Coculescu M, Grigorescu F. . FTO gene associates to metabolic syndrome in women with polycystic ovary syndrome. . Biochem Biophys Res Commun. Epub 2008 Jun 20. , 373(2), pp. 230-234, 2008.
• Coculescu M, Niculescu D, Lichiardopol R, Purice M. . Insulin resistance and insulin secretion in non-diabetic acromegalic patients. Exp Clin Endocrinol Diabetes, 115(5), pp. 308-316, 2007.
• Coculescu M. Blood-brain barrier for human growth hormone and insulin-like growth factor-I. . J Pediatr Endocrinol Metab. , 12(2), pp. 113-124, 1999.
• Catrina SB, Catrina AI, Sirzén F, Griffiths W, Bergman T, Biberfeld P, Coculescu M, Mutt V. . A cytotoxic, apoptotic, low-molecular weight factor from pineal gland. . Life Sci. , 65(10), pp. 1047-1057, 1999.
• Badiu C, Coculescu M, Moller M. . Arginine vasotocin mRNA revealed by in situ hybridization in bovine pineal gland cells. . Cell Tissue Res. 1999 Feb; 295(2):225-9. , 295(2), pp. 225-229, 1999.
• Mihai R, Coculescu M, Wakerley JB, Ingram CD. . The effects of [Arg8]vasopressin and [Arg8]vasotocin on the firing rate of suprachiasmatic neurons in vitro. . Neuroscience. , 62(3), pp. 783-792, 1994.
• Haulica I, Coculescu M, Ghinea E, Stratone A, Petrescu G, Rosca V, Oprescu M. . Biosynthesis of isorenin in cell cultures from pineal glands of adult and newborn rats. . Life Sci. , 27(10), pp. 809-813, 1980.
• Coculescu M, Serbanescu A, Temeli E. . Influence of arginine vasotocin administration on nocturnal sleep of human subjects. Waking Sleeping. , 3(33), pp. 273-277, 1979.
• Coculescu M, Matulevicius V, Goldstein R, Pavel S. . Presence and synthesis of vasotocin in the pineal gland of Brattleboro rats. . J Endocrinol. , 77(1), pp. 145-146, 1978.
• Coculescu M, Oprescu M, Zagrean L. . Angiotensin I-like immunoreactive substance in pineal gland of normal and Brattleboro rats with hereditary diabetes insipidus. . Physiologie. 1977 , 14(1), pp. 47-51, 1977.
• Coculescu M, Pavel S. Arginine vasotocin-like activity of cerebrospinal fluid in diabetes insipidus. Journal of Clinical Endocrinology and Metabolism, 36(5), pp. 1031-1032, 1973.
• Pavel S., Coculescu M. " Arginine Vasotocin-Like Activity of Cerebrospinal Fluid Induced by Injection of Hypertonic Saline into the Third Cerebral Ventricle of Cats" . Endocrinology (USA), 91, pp. 825-827, 1972.


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