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>> Românã

Manuela Banciu

Babes-Bolyai University, Faculty of Biology and Geology, Dept. Experimental Biology , Cluj-Napoca, Romania

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Born: 1974

Interests: pharmacology, biochemistry, drug delivery, nanomedicines, cancer

Manuela Banciu was born on 26th May 1974, in Sighisoara, Romania. From 1989 to
1992, she attended the secondary school at Gheorghe Marinescu College in Targu
Mures, Romania. In 1997 she graduated Biology at the Faculty of Biology and
Geology, Babes-Bolyai University of Cluj-Napoca, Romania. One year later, she
obtained a Master Degree in Cell and Molecular Biology at the same University.
During 5 years (1997 - 2002) she was employed as microbiologist, at S.C. Terapia
S.A., one of the largest pharmaceutical companies in Romania. Since 2002 she has
been appointed as teaching assistant in Biochemistry and Cytology at the Department
of Experimental Biology, Faculty of Biology and Geology, Cluj-Napoca, Romania. In
December 2004 she was awarded with a Traveling Grant (Company of Biologists,
UK) at the Department of Pharmaceutics, Utrecht Institute for Pharmaceutical
Sciences (UIPS), Utrecht University, The Netherlands. In January 2005 she was
granted with a 1-year Galenos Marie Curie Fellowship at the same University.In June
2006 she has started her PhD project on antitumor effects of glucocorticoids
encapsulated in long-circulating liposomes under the supervision of Professor Dr
Gert Storm and Dr Raymond Schiffelers, at the same Department.
The doctoral thesis was defended in 2007 at Utrecht University, The Netherlands.

ResearcherID: D-6425-2011

Selected publications:
• Lobatto ME, Fayad ZA, Silvera S, Vucic E, Calcagno C, Mani V, Dickson SD, Nicolay K, Banciu M, Schiffelers RM, Metselaar JM, van Bloois L, Wu HS, Fallon JT, Rudd JH, Fuster V, Fisher EA, Storm G, Mulder WJ. . Multimodal Clinical Imaging To Longitudinally Assess a Nanomedical Anti-Inflammatory Treatment in Experimental Atherosclerosis. . Mol Pharm. , 7(6), pp. 2020-2029, 2010.
• Coimbra M, Banciu M, Fens MH, de Smet L, Cabaj M, Metselaar JM, Storm G, Schiffelers RM. . Liposomal pravastatin inhibits tumor growth by targeting cancer-related inflammation. . J Control Release, 148(3), pp. 303-10, 2010.
• Banciu, M., Schiffelers, R. M., Storm, G. . Investigation into the role of tumor-associated macrophages in the antitumor activity of Doxil. Pharm Res. , 25(8), p. 1948–1955, 2008.
• Banciu, M., Metselaar, J. M., Schiffelers, R. M., Storm, G. . Liposomal glucocorticoids as tumor-targeted anti-angiogenic nanomedicine in B16 melanoma-bearing mice. . Journal of Steroid Biochemistry and Molecular Biology , 111(1-2), pp. 101-110 , 2008.
• Banciu, M., Fens, M. H. M., Storm, G., Schiffelers, R. M. . Antitumor activity and tumor localization of liposomal glucocorticoids in B16 melanoma-bearing mice. . J. Control. Release. , 127(2), pp. 131-6., 2008.
• Banciu, M., Schiffelers, R. M., Metselaar, J. M., Storm, G. . Utility of Targeted Glucocorticoids in Cancer Therapy. . J Liposome Res. , 18(1), pp. 47-57, 2008.
• Banciu, M., Metselaar, J. M., Schiffelers, R. M., Storm, G. . Antitumor activity of liposomal prednisolone phosphate depends on the presence of functional tumor-associated macrophages in tumor tissue. . Neoplasia, 10 (2), pp. 108-17, 2008.
• Banciu, M. . “Liposomal Targeting of Glucocorticoids to Inhibit Tumor Angiogenesis”. 2007.
• Schiffelers, R. M., Banciu, M., Metselaar, J. M., Storm, G. . Therapeutic application of long-circulating liposomal glucocorticoids in auto-immune diseases and cancer. . J Liposome Res. , 16 (3), pp. 185-194., 2006.
• Banciu, M., Schiffelers, R. M., Fens, M. H. A. M., Metselaar, J. M., Storm, G. . Anti-angiogenic effects of liposomal prednisolone phosphate on B16 melanoma in mice. J. Control. Release. , 113 (1), pp. 1-8 , 2006.


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