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Claudia Cosmineanu-Halaby

Winthrop University Hospital, New York, USA

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Born: 1973

Interests: Pediatrics; Pulmonary Pediatrics; Lead poisoning in children; Human Parainfluenza Virus Type 3 infectivity; Respiratory Syncytial Virus infection

Details:
Board certified Pediatrician
Pediatric Pulmonary Fellow- Winthrop University Hospital, Mineola, NY
Assistant Clinical Instructor- Pediatrics- Stony Brook Medical School, Stony Brook, NY

2009- present
on-going research -Respiratory Syncytial Virus infection

2005-2009 Residency/Chief Resident- Mount Sinai Medical School at Elmhurst Hospital Center
Co-investigator in the following research studies at Elmhurst Hospital Center:
1)Lead in Pregnancy: Universal Screening is Necessary
2)Blood Lead Changes During the First Two Years of Life in Infants Born to Women with High Blood Lead Concentrations.
3)High Serum Lead Levels in Newborns and Clinical Implications in the First Three Years of Life.
4)High Lead Levels in Newborns and Brain Development; a study in collaboration with the Center for Disease Control (CDC).

2004-2005
Post-doctoral Fellowship- Mount Sinai School of Medicine: Parainfluenza Virus type 3, a study of virus infectivity with insights into receptor binding and fusion mechanisms
Pediatrics Department, Mount Sinai Hospital, New York
•I investigated the infectivity of Human Parainfluenza Virus Type 3 (HPIV3), a virus involved in the pathogenesis of croup, bronchiolitis and pneumonia in children.
•I studied two HPIV3 envelop proteins: HN; the protein by which the virus attaches to the host cell, and F; the fusion protein by which the virus is able to penetrate the host cell.
•I designed and express different mutants of the HN-binding protein in order to study the way the virus infects cells
•I designed and purify different mutant HPIV3 proteins to find highly immunogenic viral proteins that can be used to create a vaccine against this virus.

2003- Post-doctoral Fellowship-Mount Sinai School of Medicine: Gene suppression effect of Diethylstilbestrol in the developing female reproductive tract
Molecular Biology Department, Mount Sinai Hospital, New York, NY
•I investigated the genes expressed in the female reproductive tract from the fetal to pre-adult period.
•I described the genetic implications of Diethylstilbestrol treatment and I extrapolated the effect of gene suppression on the genesis of cancer in the child female reproductive tract.



Selected publications:
• T. Gabinsky, A. Ittoop, C. Cosmineanu, G. Stefanov, M. Gertner. Lead in Pregnancy: A Universal Screening – Is it Necessary. In Pediatric Academic Societies’ Annual Meeting, Toronto, Canada (May3-8, 2007). 2007.
• T. Gabinsky, A. Ittoop, C. Cosmineanu, G. Stefanov, M. Gertner. Blood Lead Changes During First Two Years of Life in the Infants Born to Women with High Lead Concentration. In Pediatric Academic Societies’ Annual Meeting, Toronto, Canada (May3-8, 2007). 2007.


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